All-In E37: NYC rejects far-left candidates, new developments in lab leak theory, App Store breakup & more

NYC Mayoral Race & Eric Adams

• Eric Adams, former NYPD officer and borough president, leads Democratic primary with 32% of first-place votes
• Discussion centered on Adams' moderate, tough-on-crime stance resonating with voters
• The hosts highlighted how Adams successfully defended his position on "stop, question and frisk" despite attempts to mischaracterize his stance
• Sacks noted this demonstrates Twitter is not real life, with Adams (14k followers) beating Yang (2M followers)

COVID Lab Leak Theory Updates

• New evidence emerged about deleted COVID genomic sequences from early cases in China
• Friedberg explained how a researcher named Jesse Bloom discovered deleted sequences and recovered them from Google Cloud
• Discussion of potential US involvement in sequence deletion raised questions about institutional relationships
• Debate over whether investigating origins matters vs focusing on future prevention

Apple App Store & Antitrust

• House Judiciary Committee discussed bills that would force Apple to allow third-party app stores
• Chamath and Sacks supported breaking Apple's monopoly, arguing it would benefit startups
• Friedberg dissented, arguing government intervention could harm innovation
• Discussion of how Apple's 30% take rate may have overplayed their hand, creating powerful enemies like Epic Games and Spotify

Notable Exchanges

• Extended discussion about the podcast format and role of sound bites
• Debate over whether tech monopolies can be disrupted naturally or require government intervention
• Antonio Garcia Martinez's article about Apple discussed, with agreement that current Apple lacks innovation of Jobs era

The episode concluded with personal updates including Sacks' diet progress and banter about potential podcast monetization.